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c erbB 2 Proto Oncogenes

《英文msh詞典》c erbB 2 Proto Oncogenes
[入口詞] c erbB 2 Proto Oncogenes
[主題詞] Genes,erbB-2
[英文釋義] The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR,ERBB-2),a protein with structural features simular to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythoblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.

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